Not to be confused with sixth disease. See Exanthema subitum. Erythema infectiosum or fifth disease is one of several possible manifestations of infection by. Erythema infectiosum (fifth disease). Erythema infectiosum is a mild childhood disease that is caused by human parvovirus B This condition. A general overview of the symptoms, causes and treatment of fifth disease, and other useful tips for parents.

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The bright red rash most commonly appears in the face, particularly the cheeks. The affected joints are usually symmetric. Servant-Delmas A, Morinet F. No specific therapy is recommended. Typically, school children, day-care workers, teachers, and parents are most likely to be exposed to the virus. The disease process is typically self-limiting. This facial rash is followed by a lacy, flat rash that appears on the arms, legs, trunk and buttocks.

It looks like a “slapped cheek. Adults who get it might also have joint pain and swelling. Bol Asoc Med P R. Prevention Fifth disease is spread in the droplets of coughs and sneezes, on dirty tissues, and on drinking glasses and eating utensils. Usually, your doctor can diagnose fifth disease by seeing the typical “slapped cheek” rash without fever or other signs of illness. Listeriosis Congenital cytomegalovirus infection. Any age may be affected, although it is most common in children aged 5 to 15 years.

Differential Diagnosis Many other viral exanthems can be included in the differential diagnosis of erythema infectiosum including measles, rubella, roseola, and scarlet fever.


In adults, when arthralgias are more common, differential diagnosis can include influenza and mononucleosis. Infected children and adults will be contagious from as much as seven days before and right up to the moment the characteristic rash may appear. Slapped cheek syndrome, slapcheek, slap face, slapped face [1] [2]. Treatment Since fifth disease is a mild illness, it usually does not require treatment.

Parvovirus B19 infection in pregnant patients can have severe fetal complications. Unusual skin manifestations associated with parvovirus B19 primary infection in This is a defining symptom of the infection in children hence the name “slapped cheek disease”. This page was last edited on 19 Decemberat Fifth disease spreads easily, through saliva and mucus. Clinical heterogeneity of human parvovirus B19 infection following adult liver Acute infection and exposure to a fetus can be fatal.

Since fifth disease is a mild illness, it usually does not require treatment.

IgM antibodies can usually be found within 7 to 10 days of virus exposure. Outbreaks dissase fifth disease typically occur in late winter and early spring.

Understanding Fifth Disease (Erythema Infectiosum) | Montreal Children’s Hospital

Quach, Fifth disease is usually considered to be mild. Patients are usually no longer infectious once the rash has appeared. IgG antibodies will start to rise about 2 weeks after viral exposure, and the patient will confer immunity as these will then be measurable for life. This rash does vifth develop early in the disease process. Parvovirus B19 is transmitted most commonly through respiratory droplets into cells in the respiratory tract.


Fifth Disease (Erythema Infectiosum) Guide: Causes, Symptoms and Treatment Options

Although joint pains in adolescents may last for a few weeks or months, there are typically no long-term joint problems. Testing can be obtained via bloodwork for specific antibodies. This can range from ddisease symptoms to non-specific flu-like symptoms to the classic symptoms of facial rash and arthralgias. Older children and adults with fifth disease may have inectiosum in walking and in bending joints such as wrists, knees, ankles, fingers, and shoulders.

In addition, pregnant women who contract the virus may pass the infection to the fetus in some cases.

Fifth disease

Mediterr J Hematol Infect Dis. Kids are not just little people.

It is especially important to wash your hands before you eat and after you have touched contaminated items dirty tissues, drinking glasses, eating utensils. Occasionally, the rash will extend over the bridge of the nose or around the mouth. At the time the facial rash develops, the patient usually feels well, and the viremia has resolved.

Fifth Disease

Fetal death risk is highest infectiosu infected pregnant patients under 20 weeks gestational age. Transmission can also occur via blood exposure.

Women are more affected by joint symptoms than men. Samanta D, Willis E.