Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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Treatment for Nasopharyngeal angiofibroma JNA is primarily surgical. These features along with the specific age and sex predilection can help in differentiating JNA from other nasopharyngeal lesions. Overlying mucosa appeared normal. Srivalli Madhira 1 Department of E.

Juvenile nasopharyngeal angiofibroma

Because these tumors are benign, metastasis to distal sites does not occur. Epistaxis was the most distressing symptom of all which made the patients to seek medical advice early. Several reports suggest that JNA regresses over time. JNA is benign but locally destructive.

Nasopharyngeal angiofibroma – Wikipedia

Two types of lateral extension in juvenile nasopharyngeal angiofibroma: Cases and figures Imaging differential diagnosis. During surgery, it was found that case no. Molecular pathogenesis of juvenile nasopharyngeal angiofibroma in Brazilian patients.


Angiofiboma intonation of voice, rhinolalia clausa, was observed in 5 cases case nos. These techniques help to establish the exact site, extension and relation of the tumor to the adjacent structures such as blood vessels and nerves.

Moorthy 1 Department of E.

The smaller vessels in the central portion of the lesion typically lack muscular elastic laminae and the absence of muscular coat contributes to the capacity for massive bleeding that occurs with JNA [ 3 ]. W B Saunders Co. Prognosis for nasopharyngeal angiofibroma is favorable. Exclusively endoscopic removal of juvenile nasopharyngeal angiofibroma: The duration of surgery reduced considerably and there was no need for a prolonged post nasal pack.

A wait and watch policy with periodic imaging may thus postpone or eliminate the need for surgery and reduce morbidity. JNA’s sex selectivity and the relatively young age at diagnosis suggest that its development is hormone dependent.

Partial maxillectomy was done in case no 1 and 6. Strayer; Emanuel Rubin It was mucoid to mucopurulent. Their visual acuity was normal. Nasal cavity Esthesioneuroblastoma Nasopharynx Nasopharyngeal carcinoma Nasopharyngeal angiofibroma Larynx Laryngeal cancer Laryngeal papillomatosis. Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys.

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Mast cells and T-lymphocytes in juvenile angiofibromas.

Nasopharyngeal angiofibroma

Author information Article notes Copyright and License information Disclaimer. Markers of vascular differentiation, proliferation and tissue remodeling in juvenile nasopharyngeal angiofibromas. Although angiofibroma is histologically angiofivroma, it may act in an aggressive fashion characterized by recurrences that may extend into and destroy the adjacent bony structures.

Genetic alterations in juvenile nasopharyngeal angiofibromas. The infratemporal fossa approach for nasopharyngeal tumors. As this tumor is aggressive and expansile, it invades adjacent structures causing further symptoms.